| A.Villa | 3 : 1 | C Palace | gol: Agbonlahor (testa), Ambrose (rigore), Carew (2 rigore) |
| Tottenham | 4 : 0 | Bolton | gol: Pavlyuchenko, Jääskeläinen (autorete), O'Brien (autorete) |
| Stoke City | 3 : 1 | Man.City | gol: Kitson, Bellamy, Shawcross (testa), Sanli -- DTS -- car. rosso: Adebayor |
| West Brom | 2 : 3 | Reading | gol: Koren, Kébé, Howard, Sigurðsson -- DTS -- |
| C Palace | 2 : 2 | A.Villa | gol: Ertl (testa), Collins (testa), Ambrose (punizione), Petrov (testa). 2 assist Downing |
| Fulham | 4 : 0 | Notts Co | gol: Davies, Zamora, Duff, Okaka Chuka |
| Bolton | 1 : 1 | Tottenham | gol: Davies, Defoe, Huddlestone rigore sbagliato) |
| Man.City | 1 : 1 | Stoke City | gol: Wright-Phillips, Fuller (testa) |
| Derby | 1 : 2 | Birminghm | gol: McEveley, Dann (testa), Ridgewell |
| Reading | 2 : 2 | West Brom | gol: Kébé, Koren, Church, Mattock car. rosso: Long, Mulumbu |
| Southmptn | 1 : 4 | Portsmth | gol: Owusu Abeyie, Lambert (testa), Dindane, Belhadj, O'Hara. 2 assist Owusu Abeyie |
| Chelsea | 4 : 1 | Cardiff | gol: Drogba, Chopra (testa), Ballack, Sturridge, Kalou (testa) |
